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Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.

Huntington's disease (HD) is a neurodegenerative disease caused by the expansion of a poly-glutamine (poly-Q) stretch in the huntingtin (Htt) protein. G...

Stars: 129 Updated: January 23rd,2018

Localisation of P2X Receptors in HSG and HEK cells by SDS-PAGE/Western blotting and immunofluorescence

react-text: 644 P2X receptors that are gated by extracellular ATP are among the few known examples of ligand-gated cation-selective channels. There have been seven cloned proteins identified to date as members of the P2X receptor fami...

Stars: 133 Updated: January 23rd,2018

Expression and localisation of stanniocalcin 1 in rat bladder, kidney and ovary.

Abstract Bony fish use the glycoprotein hormone stanniocalcin (STC) to counteract hypercalcaemia. This is achieved through dual mechanisms involving gil...

Stars: 104 Updated: January 23rd,2018

Quantitative immunofluorescence microscopy of subcellular GLUT4 distribution in human skeletal muscle: effects of endurance and spri...

Increases in insulin‐mediated glucose uptake following endurance training (ET) and sprint interval training (SIT) have in part been attributed to conco...

Stars: 176 Updated: January 23rd,2018

Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: a novel sui...

Nitric oxide (NO(*)) has many characteristics including cytotoxicity, radiosensitization and anti-angiogenesis, which make it an attractive molecule for...

Stars: 176 Updated: January 23rd,2018

Identification and localisation of ATP P2X receptors in rat midbrain

P2X receptors that are gated by extracellular ATP are among the few known examples of ligand-gated cation-selective channels. There have been seven clon...

Stars: 88 Updated: January 23rd,2018

Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer.

Abstract Nitric oxide synthase gene therapy has been shown to be effective at inducing apoptosis in experimental tumours and sensitizing them to radioth...

Stars: 116 Updated: January 23rd,2018

Diagnosis of congenital disorders of glycosylation type-I using protein chip technology

A method for the diagnosis of the congenital disorders of glycosylation type I (CDG-I) by SELDI-TOF-MS of serum transferrin immunocaptured on protein ch...

Stars: 113 Updated: January 23rd,2018

Large-Scale Cultivation of Acidophilic Hyperthermophiles for Recovery of Secreted Proteins

An electric water heater was modified for large-scale cultivation of aerobic acidophilic hyperthermophiles to enable recovery of secreted proteins. Crit...

Stars: 117 Updated: January 23rd,2018

Analysis of novel P2X subunit‐specific antibodies in rat cardiac and smooth muscle

Abstract P2X receptors are cation-selective channels gated by extracellular adenosine triphosphate (ATP). There are relatively few known types of ligand...

Stars: 109 Updated: January 23rd,2018

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